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  1. L-arginine is the common substrate for the two isoforms of arginase. Arginase I, highly expressed in the liver and arginase II mainly expressed in the kidney. Arginase I-producing myeloid derived suppressor ce...

    Authors: David J Tate Jr, Derek J Vonderhaar, Yupanqui A Caldas, Toye Metoyer, John R Patterson IV, Diego H Aviles and Arnold H Zea
    Citation: Journal of Hematology & Oncology 2008 1:14
    Content type: Research Published on:

  2. The most common semiquantitative method of evaluation of pulmonary lesions using 18F-FDG PET is FDG standardized uptake value (SUV). An SUV cutoff of 2.5 or greater has been used to differentiate between benign a...

    Authors: Majid Khalaf, Hani Abdel-Nabi, John Baker, Yiping Shao, Dominick Lamonica and Jayakumari Gona
    Citation: Journal of Hematology & Oncology 2008 1:13
    Content type: Research Published on:

  3. Amplification of the ERBB2 (Her-2/neu) oncogene, which occurs in approximately 25% of breast carcinomas, is a known negative prognostic factor. Available data indicate that a variable number of nearby genes on ch...

    Authors: Lydia Usha, Bita Tabesh, Larry E Morrison, Ruta D Rao, Kris Jacobson, April Zhu, Sanjib Basu and John S Coon
    Citation: Journal of Hematology & Oncology 2008 1:12
    Content type: Research Published on:

  4. In recent years, new treatment for renal cell carcinoma (RCC) has been a spotlight in the field of cancer therapeutics. With several emerging agents branded as 'targeted therapy' now available, both medical on...

    Authors: David Chu and Shenhong Wu
    Citation: Journal of Hematology & Oncology 2008 1:11
    Content type: Review Published on:

  5. Molecular characterisation of normal karyotype acute myeloid leukemia (NK-AML) allows prognostic stratification and potentially can alter treatment choices and pathways. Approximately 45–60% of patients with N...

    Authors: Angela YC Tan, David A Westerman, Dennis A Carney, John F Seymour, Surender Juneja and Alexander Dobrovic
    Citation: Journal of Hematology & Oncology 2008 1:10
    Content type: Short report Published on:

  6. Previous studies demonstrated Ganoderma lucidum polysaccharides (GL-PS), a form of bioactive β-glucan can stimulate the maturation of monocyte-derived dendritic cells (DC). The question of how leukemic cells espe...

    Authors: Wing Keung Chan, Christopher Ching Hang Cheung, Helen Ka Wai Law, Yu Lung Lau and Godfrey Chi Fung Chan
    Citation: Journal of Hematology & Oncology 2008 1:9
    Content type: Research Published on:

  7. In a departure from conventional strategies to improve treatment outcome for myeloid malignancies, we report the isolation of leukemia-specific peptides using a phage display library screened with freshly obta...

    Authors: Naomi Galili, Emmanuelle Devemy and Azra Raza
    Citation: Journal of Hematology & Oncology 2008 1:8
    Content type: Research Published on:

  8. To report the clinico-histopathologic features, management and outcome of Rosai-Dorfman disease of the orbit.

    Authors: Geeta K Vemuganti, Milind N Naik and Santosh G Honavar
    Citation: Journal of Hematology & Oncology 2008 1:7
    Content type: Research Published on:

  9. Histone deacetylase (HDAC) inhibitors are a new class of chemotherapeutic agents. Our laboratory has recently reported that phenylhexyl isothiocyanate (PHI), a synthetic isothiocyanate, is an inhibitor of HDAC...

    Authors: Quanyi Lu, Xianghua Lin, Jean Feng, Xiangmin Zhao, Ruth Gallagher, Marietta Y Lee, Jen-Wei Chiao and Delong Liu
    Citation: Journal of Hematology & Oncology 2008 1:6
    Content type: Research Published on:

  11. Lipoic acid (LA), a potent antioxidant, has been used as a dietary supplement to prevent and treat many diseases, including stroke, diabetes, neurodegenerative and hepatic disorders. Recently, potent anti-tumo...

    Authors: Elangovan Selvakumar and Tze-chen Hsieh
    Citation: Journal of Hematology & Oncology 2008 1:4
    Content type: Research Published on:

  13. Detection of circulating tumor cells (CTC) in the blood of cancer patients may have prognostic and predictive significance. However, background expression of 'tumor specific markers' in peripheral blood mononu...

    Authors: Fanglei You, Lisa A Roberts, S Peter Kang, Raquel A Nunes, Cinara Dias, J Dirk Iglehart, Natalie A Solomon, Paula N Friedman and Lyndsay N Harris
    Citation: Journal of Hematology & Oncology 2008 1:2
    Content type: Research Published on:
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Journal of Hematology & Oncology

ISSN: 1756-8722

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