Fig. 2
From: Nanomaterials-driven in situ vaccination: a novel frontier in tumor immunotherapy

The TME is immunosuppressive. Abbreviations: DC, dendritic cell; tol, tolerogenic; IDO, indoleamine 2,3-dioxygenase; Arg, arginase; MDSC, myeloid-derived suppressor cell; NOX-2, nitric oxide synthase-2; PD(L)1, programmed death (ligand)-1; NO, nitric oxide; Treg, regulatory T cell; IL, interleukin. Copyright 2020, Int J Hyperthermia