Table 4 TEAEs of all grades (in ≥ 20% patients) and grade 3/4 severity (in ≥ 5% patients)
AE, n (%) | All Grades (N = 67) | Grade 3/4 (N = 67) |
|---|---|---|
Patients with any AE | 65 (97) | 60 (90) |
Hematologic AE | ||
Platelet count decreased | 26 (39) | 25 (37) |
Red blood cell count decreased | 18 (27) | 17 (25) |
Neutrophil count decreased | 17 (25) | 16 (24) |
White blood cell count increased | 17 (25) | 7 (10) |
Febrile neutropenia | 16 (24) | 13 (19) |
White blood cell count decreased | 7 (10) | 4 (6) |
Non-hematologic AE | ||
Nausea | 35 (52) | 3 (4) |
Constipation | 28 (42) | 2 (3) |
Vomiting | 27 (40) | 3 (4) |
Diarrhea | 21 (31) | 1 (1) |
Fatigue | 21 (31) | 7 (10) |
Hypokalemia | 18 (27) | 4 (6) |
Headache | 17 (25) | 1 (1) |
Decreased appetite | 16 (24) | 0 |
Cough | 15 (22) | 1 (1) |
Pyrexia | 15 (22) | 0 |
Hypertension | 8 (12) | 4 (6) |
Pneumonia | 8 (12) | 4 (6) |