Fig. 1

Duration of response for patients with CR/CRh compared to other responders. a Kaplan–Meier plot of duration of response comparing patients with best overall response (BOR) of CR/CRh (n = 21) vs other responders (n = 13). Other responders include patients with BOR of CRi, MLFS, and PR. b Swimmer plot of individual patients by responder (PR or better) or non-responder with their duration of treatment represented by the colored bar and duration of follow-up represented by the line. The color of the bar denotes the best overall response. The open circle is the time of first response, the diamond represents a progressive disease event and the closed circle represents a death event. Prior exposure to a hypomethylating agent (HMA) or IDH inhibitor (IDH1i) therapy is marked with an X in the corresponding column next to the lane. Other responders are patients with a best overall response of CRi, MLFS, or PR. CR, complete remission; CRh, CR with partial hematologic recovery; CRi, CR with incomplete recover; MLFS, morphologic leukemia-free state; PR, partial remission; NE, not evaluable; PD, progressive disease; SD, stable disease