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Table 1 The all age incidence/death cases and age-standardized incidence/death rate of both sexes neoplasms in global

From: Global burden of cancer and associated risk factors in 204 countries and territories, 1980–2021: a systematic analysis for the GBD 2021

 

1990

 

2021

 

1980

 

2021

 

Type of neoplasms

All age incidence cases No. (95% UI)

Age-standardized incidence rate per 100,000 (95% UI)

All age incidence cases No. (95% UI)

Age-standardized incidence rate per 100,000 (95% UI)

All age death cases No. (95% UI)

Age-standardized death rate per 100,000 (95% UI)

All age death cases No. (95% UI)

Age-standardized death rate per 100,000 (95% UI)

Neoplasms

34,774,679.41 (30,034,912.81,40,425,534.96)

758.26 (658.68,869.22)

66,479,607.27 (58,335,731.4,74,980,442.95)

790.33 (694.43,893.01)

4,796,347.41 (4,549,260.7,5,084,876.75)

153.52 (145.3,162.15)

9,888,413.46 (9,124,879.13,10,585,373.15)

116.49 (107.28,124.69)

Bladder cancer

260,141.8 (242,823.27,272,206.57)

6.9 (6.46,7.23)

540,309.73 (494,720.89,582,579.44)

6.35 (5.8,6.85)

98,391.26 (90,284.72,105,045.92)

3.59 (3.31,3.82)

221,888.32 (200,567.17,242,326.46)

2.68 (2.42,2.93)

Brain and central nervous system cancer

173,086.44 (147,452.47,194,951.22)

3.75 (3.21,4.21)

357,482.3 (310,456.68,407,432.57)

4.28 (3.71,4.88)

106,990.82 (89,747.36,126,261.59)

2.89 (2.45,3.35)

258,626.8 (222,185.21,296,133.94)

3.06 (2.62,3.5)

Breast cancer

875,657.23 (834,228.9,910,528.91)

21.38 (20.27,22.22)

2,121,564.32 (1,982,142.64,2,268,722.63)

24.56 (22.93,26.26)

281,432.61 (265,487.27,297,309.39)

9.08 (8.53,9.56)

674,199.41 (623,371.55,720,822.55)

7.9 (7.27,8.44)

Cervical cancer

409,548.49 (383,207.24,438,505.58)

9.25 (8.65,9.91)

667,426.4 (613,030.09,726,422.07)

7.79 (7.16,8.48)

199,543.83 (182,793.46,224,433.73)

5.96 (5.48,6.69)

296,667.24 (272,058.62,321,905.72)

3.44 (3.16,3.73)

Colon and rectum cancer

916,583.53 (866,238.31,951,894.97)

24.04 (22.54,25.01)

2,194,143.25 (2,001,271.82,2,359,390.09)

25.61 (23.32,27.52)

462,372.65 (420,618.76,499,011.02)

16.03 (14.7,17.27)

1,044,072.21 (950,187.61,1,120,169.34)

12.4 (11.24,13.31)

Esophageal cancer

354,730.82 (317,512.39,388,914.46)

8.86 (7.96,9.69)

576,529.28 (509,492.07,645,648.46)

6.65 (5.88,7.45)

299,718.68 (260,955.36,341,533.62)

9.5 (8.3,10.78)

538,601.91 (475,943.98,603,405.55)

6.25 (5.53,7)

Eye cancer

18,002.21 (14,772.09,21,233.11)

0.4 (0.33,0.47)

33,950.77 (26,532.91,39,857.27)

0.42 (0.33,0.5)

6656.88 (5145.73,7857.55)

0.18 (0.14,0.2)

10,432.79 (8013.52,12,230.91)

0.13 (0.1,0.16)

Gallbladder and biliary tract cancer

107,797.75 (96,890.17,117,511.81)

2.89 (2.59,3.15)

216,768.35 (181,887.99,245,237.6)

2.56 (2.16,2.89)

78,620.48 (69,424.31,87,848.72)

2.7 (2.4,2.99)

171,961.17 (142,351.85,194,238.42)

2.04 (1.7,2.29)

Hodgkin lymphoma

54,671.44 (45,648.57,59,832.16)

1.12 (0.93,1.23)

65,182.01 (53,167.43,77,142.98)

0.79 (0.64,0.94)

28,670.69 (21,558.13,32,505)

0.78 (0.6,0.89)

28,179.99 (20,895.4,35,652.96)

0.34 (0.25,0.43)

Kidney cancer

159,774.29 (154,831.25,163,926.28)

3.89 (3.75,3.99)

387,828.72 (365,359.71,406,635.25)

4.52 (4.26,4.75)

58,851.77 (56,258.4,61,270.66)

1.88 (1.81,1.95)

161,194.54 (150,317.57,169,348.28)

1.91 (1.78,2.01)

Larynx cancer

125,175.07 (118,981.12,131,639)

3.07 (2.92,3.23)

200,883.04 (186,941.11,216,097.56)

2.29 (2.13,2.47)

71,052.78 (65,958.77,77,167.26)

2.22 (2.06,2.4)

117,251.6 (109,354.57,125,952.42)

1.35 (1.26,1.45)

Leukemia

311,647.62 (278,619.9,343,177.37)

6.89 (6.22,7.49)

461,422.73 (397,547.9,504,397.01)

5.63 (4.83,6.17)

221,449.6 (190,958.64,255,967.69)

5.95 (5.26,6.7)

320,283.63 (274,969.49,349,049.9)

3.89 (3.34,4.25)

Lip and oral cavity cancer

174,077.49 (167,404.23,181,621.61)

4.27 (4.1,4.45)

421,577.11 (389,878.79,449,782.06)

4.88 (4.52,5.2)

75,530.83 (70,956.24,81,724.77)

2.4 (2.26,2.58)

208,379.43 (191,287.97,224,162.08)

2.42 (2.23,2.6)

Liver cancer

244,689.36 (224,795.5,268,548.98)

5.9 (5.43,6.48)

529,202.46 (480,339.46,593,849.1)

6.15 (5.58,6.9)

203,098.32 (170,622.75,235,838.89)

6.17 (5.21,7.18)

483,875.13 (440,400.32,540,177.12)

5.65 (5.13,6.3)

Malignant neoplasm of bone and articular cartilage

46,583.02 (42,150.54,54,215.43)

0.97 (0.89,1.13)

91,375.06 (73,780.37,102,469.66)

1.11 (0.9,1.25)

32,403.82 (29,160.57,37,214.64)

0.9 (0.82,1.02)

66,114.26 (53,305.43,74,466.88)

0.79 (0.64,0.89)

Malignant skin melanoma

124,319.84 (119,603.87,127,610.46)

2.98 (2.87,3.06)

303,104.61 (281,717.64,318,904.82)

3.56 (3.31,3.75)

24,355.42 (22,280.52,26,020.01)

0.78 (0.72,0.84)

61,549.73 (54,852.45,66,265.02)

0.73 (0.65,0.79)

Mesothelioma

16,493.16 (15,324.92,17,783.42)

0.42 (0.39,0.46)

31,907.89 (29,643.13,34,115.3)

0.37 (0.35,0.4)

12,539.91 (11,012.23,14,190.21)

0.42 (0.37,0.47)

29,618.93 (27,424.48,31,764.63)

0.35 (0.32,0.38)

Multiple myeloma

55,710.1 (52,022.49,59,687.84)

1.47 (1.37,1.57)

148,754.63 (131,780.43,162,049.23)

1.74 (1.54,1.89)

34,293.34 (31,638.59,37,181.27)

1.18 (1.08,1.27)

116,359.63 (103,078.62,128,470.57)

1.37 (1.22,1.52)

Nasopharynx cancer

76,255.83 (68,714.02,83,570.23)

1.74 (1.56,1.9)

118,877.91 (104,836.07,135,884.37)

1.38 (1.22,1.58)

52,474.42 (44,689.83,58,899.82)

1.52 (1.29,1.7)

75,358.67 (67,515.37,83,706.34)

0.87 (0.78,0.97)

Neuroblastoma and other peripheral nervous cell tumors

5854.22 (4516.81,7643.14)

0.11 (0.08,0.14)

10,867.4 (8279.04,13,556.99)

0.15 (0.11,0.18)

2120.99 (1823.15,2582.12)

0.05 (0.04,0.06)

5193.81 (4294.57,5932.3)

0.07 (0.06,0.08)

Non-Hodgkin lymphoma

255,667.85 (242,749.28,272,800.89)

6.08 (5.76,6.48)

604,554.14 (558,229.23,648,746.23)

7.14 (6.58,7.66)

108,989.52 (99,370.61,119,491.07)

3.26 (2.99,3.57)

267,061.2 (246,094.69,288,695.72)

3.19 (2.93,3.44)

Non-melanoma skin cancer

1,661,643.97 (1,430,711.62,1,901,240.26)

45.04 (39.4,50.96)

6,336,846.1 (5,744,729.38,6,896,046.6)

74.1 (67.32,80.69)

17,366.52 (15,706.47,19,334.37)

0.67 (0.61,0.74)

56,913.23 (48,761.35,63,037.42)

0.69 (0.59,0.77)

Other malignant neoplasms

205,977.17 (184,968.46,222,043.27)

4.86 (4.38,5.22)

422,295.02 (380,537.15,462,634.87)

5 (4.51,5.49)

120,758.75 (105,957.87,135,933.28)

3.65 (3.25,4.05)

222,208.37 (199,406.3,240,746.74)

2.65 (2.38,2.88)

Other neoplasms

24,715,051.69 (19,991,541.93,30,340,404.66)

505.41 (405.88,613.11)

42,913,361.9 (34,917,159.4,51,701,423.42)

515.17 (420.89,620.55)

13,822.9 (10,893.04,19,748.47)

0.55 (0.44,0.78)

55,179.07 (46,760.97,64,295.48)

0.68 (0.58,0.79)

Other pharynx cancer

64,528.86 (60,828.8,68,919.74)

1.55 (1.46,1.66)

169,819.52 (159,847.12,179,704.19)

1.93 (1.82,2.05)

33,228.64 (30,125.39,37,133.35)

1.01 (0.92,1.13)

98,435.11 (91,566.81,105,484.9)

1.13 (1.05,1.21)

Ovarian cancer

159,095.96 (145,708.88,174,055.01)

3.82 (3.51,4.15)

298,876 (270,729.82,324,501.02)

3.48 (3.15,3.78)

79,959.04 (73,868.7,88,950.3)

2.55 (2.36,2.82)

185,608.68 (167,961.98,201,012.67)

2.16 (1.95,2.34)

Pancreatic cancer

207,905.23 (196,649.42,217,778.46)

5.47 (5.16,5.73)

508,532.7 (462,090.89,547,207.62)

5.96 (5.39,6.42)

163,598.9 (152,946.45,177,770.67)

5.51 (5.13,5.96)

505,752.16 (461,224.42,543,899.41)

5.95 (5.4,6.41)

Prostate cancer

506,405.2 (480,851.38,524,697.41)

13.69 (12.96,14.19)

1,324,382.9 (1,217,320.93,1,400,222.17)

15.37 (14.13,16.25)

149,768.11 (136,473.64,159,297.28)

5.85 (5.35,6.22)

432,463.33 (381,872.79,463,645.28)

5.26 (4.65,5.64)

Soft tissue and other extraosseous sarcomas

54,630.92 (46,757.16,63,999.62)

1.21 (1.04,1.39)

96,200.96 (83,423.51,116,184.87)

1.16 (1,1.41)

27,390.17 (22,977.09,32,412.8)

0.77 (0.65,0.91)

50,203.14 (43,232,61,280.38)

0.6 (0.52,0.74)

Stomach cancer

980,899.43 (891,306.83,1,072,236.02)

24.76 (22.58,27)

1,230,232.61 (1,052,350.05,1,409,969.66)

14.33 (12.23,16.41)

827,903.85 (741,976.9,906,091.23)

26.76 (24.14,29.14)

954,373.6 (821,750.81,1,089,576.58)

11.2 (9.62,12.73)

Testicular cancer

38,833.49 (37,572.49,40,260.79)

0.75 (0.72,0.77)

91,507.38 (87,965.92,95,709.72)

1.12 (1.08,1.18)

6974.76 (6569.3,7482)

0.19 (0.17,0.2)

11,388.3 (10,770.7,12,055.62)

0.14 (0.13,0.15)

Thyroid cancer

89,885.45 (84,681.27,96,998.78)

2.06 (1.95,2.22)

249,538.02 (223,290.35,274,638.17)

2.91 (2.61,3.21)

17,886.88 (16,590.56,19,653.55)

0.59 (0.55,0.64)

44,798.54 (39,924.73,48,541)

0.53 (0.47,0.57)

Tracheal, bronchus, and lung cancer

1,132,063.62 (1,075,370.86,1,186,163.37)

28.54 (27.06,29.91)

2,280,688.22 (2,063,251.87,2,509,739.73)

26.43 (23.9,29.07)

828,845.54 (774,601.52,899,552.37)

26.36 (24.6,28.55)

2,016,547.44 (1,820,497.67,2,218,371.89)

23.5 (21.22,25.85)

Uterine cancer

191,290.85 (175,002.55,201,941.37)

4.72 (4.32,4.97)

473,613.85 (429,915.57,513,666.88)

5.41 (4.9,5.87)

49,284.71 (43,664.51,54,165.33)

1.63 (1.46,1.78)

97,672.08 (86,515.79,108,061.54)

1.14 (1.01,1.26)

Abbreviation: UI: uncertainty interval