Table 5 Comparison of WHO-HAEM4R, ICC and WHO-HAEM5 classification of histiocytic/dendritic cell neoplasms
WHO HAEM4R | ICC | WHO HAEM5 |
|---|---|---|
Histiocytic/dendritic cell neoplasms | ||
Langerhans cell neoplasms | ||
Langerhans cell histiocytosis Langerhans cell sarcoma | Langerhans cell histiocytosis Langerhans cell sarcoma | Langerhans cell histiocytosis Langerhans cell sarcoma |
Other dendritic cell neoplasms | ||
Indeterminate dendritic cell histiocytosis Interdigitating dendritic cell sarcoma | Indeterminate dendritic cell histiocytosis Interdigitating dendritic cell sarcoma | Indeterminate dendritic cell tumor Interdigitating dendritic cell sarcoma |
Histiocytic/macrophage neoplasms | ||
Disseminated juvenile xanthogranuloma Erdheim-Chester disease Histiocytic sarcoma | Disseminated juvenile xanthogranuloma Erdheim-Chester disease Rosai-Dorfman-Destombes disease ALK-positive histiocytosis Histiocytic sarcoma | Juvenile xanthogranuloma Erdheim-Chester disease Rosai-Dorfman disease ALK-positive histiocytosis Histiocytic sarcoma |
Follicular dendritic cell neoplasms | ||
Follicular dendritic cell sarcoma -Inflammatory pseudotumor-like follicular/fibroblastic dendritic cell sarcoma Fibroblastic reticular cell tumor | Follicular dendritic cell sarcoma EBV-positive inflammatory follicular dendritic cell sarcoma/fibroblastic reticular cell tumor Fibroblastic reticular cell sarcoma | Follicular dendritic cell sarcoma EBV-positive inflammatory follicular dendritic cell sarcoma Fibroblastic reticular cell tumor |